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CC-4080 bop5-1

Name: CC-4080 bop5-1
SKU: CC-4080
Availability: InStock

$30.00

From Mary Porter, University of Minnesota, April 2006

The bop (bypass of paralysis) mutants were isolated by Dutcher et al. in a pf10 background, by selection for restoration of motility. Hendrickson et al. showed that the BOP5 locus encodes the axonemal inner arm I1 intermediate chain dynein IC138, which is a WD-repeat dynein intermediate chain required for light chain assembly and regulation of flagellar bending.

Dutcher SK, Gibbons W, Inwood WB (1988) A genetic analysis of suppressors of the PF10 mutation in Chlamydomonas reinhardtii. Genetics 120:965-976

Dutcher SK, Power J, Galloway RE, Porter ME (1991) Reappraisal of the genetic map of Chlamydomonas reinhardtii. J Hered 82:295-301

Hendrickson TW, Perrone CA, Griffin P, Wuichet K, Mueller J, Yang P, Porter ME, Sale WS (2004) IC138 is a WD-repeat dynein intermediate chain required for light chain assembly and regulation of flagellar bending. Mol Biol Cell 15:5431-5442

Locus:
BOP5 [IC138]
Chromosome:
12

Dutcher SK, Gibbons W, Inwood WB (1988) A genetic analysis of suppressors of the PF10 mutation in Chlamydomonas reinhardtii. Genetics 120:965-976

Dutcher SK, Power J, Galloway RE, Porter ME (1991) Reappraisal of the genetic map of Chlamydomonas reinhardtii. J Hered 82:295-301

CC-4080 bop5-1

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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