CC-4179 uni3-1 mt-
$30.00
From Susan Dutcher, Washington University, November 2007
Phenotype: uniflagellate
The uni3 mutants have alterations in delta tubulin. This is the original mutant.
Dutcher SK, Trabuco EC (1998) The UNI3 gene is required for assembly of basal bodies of Chlamydomonas and encodes delta-tubulin, a new member of the tubulin superfamily. Mol Biol Cell 9:1293-1308
O'Toole ET, Giddings TH, McIntosh JR, Dutcher SK (2003) Three-dimensional organization of basal bodies from wild-type and delta-tubulin deletion strains of Chlamydomonas reinhardtii. Mol Biol Cell 14:2999-3012
Fromherz S, Giddings TH Jr, Gomez-Ospina N, Dutcher SK (2004) Mutations in alpha-tubulin promote basal body maturation and flagellar assembly in the absence of delta-tubulin. J Cell Sci 117(Pt 2):303-314