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CC-4380 ptx5-4/bbs4-4:: NIT1 ac14 mt-

Name: CC-4380 ptx5-4/bbs4-4:: NIT1 ac14 mt-
SKU: CC-4380
Availability: InStock

$30.00

From Deborah Cochran, George Witman lab, University of Massachusetts Medical School, November 2010, their F36

This mutant was obtained by transformation of strain 1330.1 (ac14 agg1 nit1 NIT2 mt) with pGP505m abd was characterized as “flagellar current (FC) positive, photo receptor current (PCR) positive.” Lechtreck et al. showed that it is an allele at the BBS4 locus.

Pazour GJ, Sineshchekov OA, Witman GB (1995) Mutational analysis of the phototransduction pathway of Chlamydomonas reinhardtii. J Cell Biol 131:427-440

Lechtreck KF, Johnson EC, Sakai T, Cochran D, Ballif BA, Rush J, Pazour GJ, Ikebe M, Witman GB (2009) The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella. J Cell Biol 187:1117-1132

Locus:
BBS4
Chromosome:
12

CC-4380 ptx5-4/bbs4-4:: NIT1 ac14 mt-

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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