CC-4382 ift46-1::NIT1, Supift461 OF1 mt+

$30.00

From Deborah Cochran, George Witman lab, University of Massachusetts Medical School, November 2010, their CYH6

Supift461 is a spontaneous partial suppressor for ift46-1 (CC-4375).
Cells of this strain are mostly palmelloid and have very short/stumpy flagella. However under certain growth conditions, the cells can manage to assemble flagella up to wild-type length and swim slowly.


Hou Y, Qin H, Follit JA, Pazour GJ, Rosenbaum JL, Witman GB (2007) Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella. J Cell Biol 176:653-665


  • Locus:
  • IFT46 [FAP32]
  • Chromosome:
  • 5