CC-5160 ift74-1::IFT74 rescue mt+

$30.00

From Jason Brown, George Witman lab, University of Massachusetts Medical School, October 2015

This strain was generated by transformation of ift74-1 with the plasmid pIFT74aphVIII containing wild-type IFT74 genomic sequence and the paromomycin-resistance cassette from pKS-aphVIII-lox (Heitzer and Zschoernig, 2007, BioTechniques).

This strain has restored wild-type flagella assembly.


Brown JM, Cochran DA, Craige B, Kubo T, Witman GB (2015) Assembly of IFT trains at the ciliary base depends on IFT74. Curr Biol. 25: 1583-1593


  • Locus:
  • IFT74
  • Chromosome:
  • 1