CC-4555 oda16-2 mt-
$30.00
From David Mitchell, SUNY Upstate Medical University, January 2013
Phenotype: impaired motility
This strain was generated by insertional mutagenesis with pMN24 (NIT-1) into nit1-305, cw15. Two backcrosses to 137c were used to create a strain more compatible with other 137c-background strains in crosses. It is defective in outer dynein arm assembly and swims slowly; about 10% of WT dynein levels still assemble.
Ahmed NT, Mitchell DR (2005) ODA16p, a Chlamydomonas flagellar protein needed for dynein assembly. Mol Biol Cell 16:5004-5012
Ahmed NT, Gao C, Lucker BF, Cole DG, Mitchell DR (2008) ODA16 aids axonemal outer row dynein assembly through an interaction with the intraflagellar transport machinery. J Cell Biol 183:313-322