P-262 cpDNA EcoRI (4.0 kb) er-u-1a
$30.00
Boynton-Gillham laboratory, Duke University, 1990
Chloroplast DNA EcoRI (4.0 kb) in pUC8; contains 3′ end of psbA, 5S, and 3′ exon of 23S with er-u-1a mutation from CC-64; 1.5 kb deletion in spacer between psbA and 5S
host strain: JM109
amp resistant
More information
Strain: CC-64 er-u-1a mt+
Insert: EcoRI (4.0 kb)
Genes present: psbA (exon 5), 5S rRNA, 23S rRNA (small exon)
Vector: pUC8
Bacterial host strain: JM109
Selectable marker: amp-r, white on X-gal
Origin: Amnon Lers in Boynton/Gillham lab, 1990
This is a subclone of P-261. The three KpnI fragments including the BamHI site (approx. 1.5 kb) located between the psbA and 5S genes were deleted, and the remaining two Kpn ends were religated, leaving only one KpnI site. The insert appears slightly smaller than 4 kb.
The er-u-1a mutation is a C->T change at bp 2622 in C. reinhardtii 23S rRNA gene (Lemieux numbering, equivalent to E. coli 2611), which confers erythromycin resistance in Chlamydomonas.