CC-1385 pf25 mt+
$30.00
From David Luck, Rockefeller University, February 1983, his isolation number ddm-100
Phenotype: impaired motility
Huang et al. reported that cells of pf25 mutants appear wild type in EM, but are missing one polypeptide of the radial spoke system and are deficient in another. They swim actively, but abnormally. This locus has been shown to correspond to the gene encoding the spoke stalk protein RSP11.
Huang B, Piperno G, Ramanis Z, Luck DJ (1981) Radial spokes of Chlamydomonas flagella: genetic analysis of assembly and function. J Cell Biol 88:80-88
Yang C, Yang P (2006) The flagellar motility of Chlamydomonas pf25 mutant lacking an AKAP-binding protein is overtly sensitive to medium conditions. Mol Biol Cell. 17:227-238
Yang P, Diener DR, Yang C, Kohno T, Pazour GJ, Dienes JM, Agrin NS, King SM, Sale WS, Kamiya R, Rosenbaum JL, Witman GB (2006) Radial spoke proteins of Chlamydomonas flagella. J Cell Sci 119:1165-1174