CC-5250 ida4 tpg1 mt-

$30.00

From Tomohiro Kubo, George Witman lab, University of Massachusetts Medical School, May 2016

Phenotype: reduced axonemal tubulin polyglutamylation and lacks inner arm dynein a, c, and d; impaired swimming motility

This mutant was obtained by crossing ida4 and tpg1.


Kubo T, Yanagisawa HA, Yagi T, Hirono M, Kamiya R (2010) Tubulin polyglutamylation regulates axonemal motility by modulating activities of inner-arm dyneins. Curr Biol. 20:441-5

Kubo T, Yagi T, Kamiya R (2012) Tubulin polyglutamylation regulates flagellar motility by controlling a specific inner-arm dynein that interacts with the dynein regulatory complex. Cytoskeleton 69:1059-68


  • Locus:
  • IDA4 / DII1, TPG1 / FAP267
  • Chromosome:
  • 12,17