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CC-5252 ida9 tpg1 mt+

Name: CC-5252 ida9 tpg1 mt+
SKU: CC-5252
Availability: InStock

$30.00

From Tomohiro Kubo, George Witman lab, University of Massachusetts Medical School, May 2016

Phenotype: Reduced axonemal tubulin polyglutamylation and lacks inner arm dynein c; impaired swimming motility

This mutant was obtained by crossing ida9 and tpg1.

Kubo T, Yanagisawa HA, Yagi T, Hirono M, Kamiya R (2010) Tubulin polyglutamylation regulates axonemal motility by modulating activities of inner-arm dyneins. Curr Biol. 20:441-5

Kubo T, Yagi T, Kamiya R (2012) Tubulin polyglutamylation regulates flagellar motility by controlling a specific inner-arm dynein that interacts with the dynein regulatory complex. Cytoskeleton 69:1059-68

Locus:
IDA4 / DII1, TPG1 / FAP267
Chromosome:
15,17

Kubo T, Yanagisawa HA, Yagi T, Hirono M, Kamiya R (2010) Tubulin polyglutamylation regulates axonemal motility by modulating activities of inner-arm dyneins. Curr Biol. 20:441-5

CC-5252 ida9 tpg1 mt+

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

Any opinions, findings, and conclusions or recommendations expressed on this website are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.

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