CC-5262 ida4 pf3 tpg1

$30.00

From Tomohiro Kubo, George Witman lab, University of Massachusetts Medical School, May 2016

Phenotype: reduced axonemal tubulin polyglutamylation, lacks inner arm dynein a,c, and d, and dynein regulatory complex 1; generates wild-type length flagella, impaired motility

This mutant was obtained by crossing pf3,ida4 and tpg1.


Kubo T, Yagi T, Kamiya R (2012) Tubulin polyglutamylation regulates flagellar motility by controlling a specific inner-arm dynein that interacts with the dynein regulatory complex. Cytoskeleton. 69:1059-68


  • Locus:
  • IDA4 / DII1, PF3, TPG1 / FAP267
  • Chromosome:
  • 12, 8, 17