CC-1686 vfl3 mt+
$30.00
From Jonathan Jarvik, Carnegie-Mellon University, November 1983
Phenotype: variable number of flagella
Mutation at the VFL3 locus causes defects in striated fibers associated with the basal body. Basal bodies are abnormally and variably spaced, and their orientation is disrupted. Cellular contents may be partitioned abnormally at cytokinesis. Marshall et al. reported that vfl3 mutants are defective in templated assembly of centrioles, but capable of de novo assembly.
In contrast to vfl2 mutants, the vfl3 mutant has normal levels of centrin and a stable nucleus-basal body connector. The flagella beat actively and waveform and frequency are normal, but the effective strokes can occur in any direction.
Wright RL, Chojnacki B, Jarvik JW (1983) Abnormal basal-body number, location, and orientation in a striated fiber-defective mutant of Chlamydomonas reinhardtii. J Cell Biol 96:1697-1707
Hoops HJ, Wright RL, Jarvik JW, Witman GB (1984) Flagellar waveform and rotational orientation in a Chlamydomonas mutant lacking normal striated fibers. J Cell Biol 98:818-824