CC-6006 dlu1-1 LC1 [#R4]

$30.00

From Miho Sakato-Antoku, Stephen M King lab, University of Connecticut Health, May 2023 

Phenotype: unlike the background strain, it restores LC1 expression and does not require arginine to grow; paromomycin-resistant

It was created by transforming mutant dlu1-1 arg7-8 cw15 with pFA-LC1 plasmid containing LC1 and ARG7 expression cassettes in tandem. It is designated as strain R4 in King lab.


Sakato-Antoku M, King SM. Outer-arm dynein light chain LC1 is required for normal motor assembly kinetics, ciliary stability, and motility. Mol Biol Cell. 2023 Jun 1;34(7):ar75. doi: 10.1091/mbc.E23-03-0104. Epub 2023 May 3. PMID: 37133971; PMCID: PMC10295483.


  • Locus:
  • DLU1 [DLU1]
  • Chromosome:
  • 2
  • Mutation Information:
  • Predicted Mutation Effect: