* The listed price of $30.00 for cultures and plasmids is for academic and non-profit users. Commercial and industrial users are charged $300.00 for each strain or plasmid and twice the listed price for media components. BACs and fosmids are $50.00 for academic and non-profit users and $500 for commercial/industry. For the Jonikas CLiP mutants, the price is $100.00 each for academic and non-profit users and commercial and industrial users are charged $500.00.
CC-6063 TUA1(4A)
$30.00
From Tomohiro Kubo, University of Yamanashi-Japan, August 2023
Phenotype: Lacks motility
Background: tua1(int1)
Origin: Generated by a CRISPR/Cas9 mediated gene editing; a paromomycin-resistant gene cassette was inserted into the intron 1 of TUA2 (Cre04.g216850); a hygromycin-resistant gene cassette was inserted into the region near 3’UTR of TUA1 (Cre03.g190950); four glutamate residues (E445, E447, E449, and E450) in TUA1 C-terminus region are all substituted to alanine
Kubo T, Tani Y, Yanagisawa HA, Kikkawa M, Oda T. α- and β-tubulin C-terminal tails with distinct modifications are crucial for ciliary motility and assembly. J Cell Sci. 2023 Aug 15;136(16):jcs261070. doi: 10.1242/jcs.261070. Epub 2023 Aug 17. PMID: 37519241.