CC-6095 oda7; ac17; aphVIII mt+
$30.00
From Gervette Penny, Susan Dutcher lab, Washington Univerity in St. Loius, November 2023
Genotype: oda7; ac17; ATG17:aphVIII-TG
Phenotype: Impaired mobility
This is a cross of oda7 CC-2240 with CC-5909. It requires acetate for growth and is resistant to paramomycin.
Penny GM, Dutcher SK. Gene dosage of independent dynein arm motor preassembly factors influences cilia assembly in Chlamydomonas reinhardtii. PLoS Genet. 2024 Mar 18;20(3):e1011038. doi: 10.1371/journal.pgen.1011038. PMID: 38498551; PMCID: PMC11020789.
Duquesnoy P, Escudier E, Vincensini L, Freshour J, Bridoux AM, Coste A, Deschildre A, de Blic J, Legendre M, Montantin G, Tenreiro H, Vojtek AM, Loussert C, Clément A, Escalier D, Bastin P, Mitchell DR, Amselem S. Loss-of-function mutations in the human ortholog of Chlamydomonas reinhardtii ODA7 disrupt dynein arm assembly and cause primary ciliary dyskinesia. Am J Hum Genet. 2009 Dec;85(6):890-6. doi: 10.1016/j.ajhg.2009.11.008. PMID: 19944405; PMCID: PMC2790569.