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CC-6096 oda8; ac17; aphVIII mt+

Name: CC-6096 oda8; ac17; aphVIII mt+
SKU: CC-6096
Availability: InStock

$30.00

From Gervette Penny, Susan Dutcher lab, Washington Univerity in St. Loius, November 2023

Genotype: oda8; ac17; ATG17:aphVIII-TG
Phenotype: Impaired mobility

This is a cross of oda8 CC-2242 with CC-5909. It requires acetate for growth and is resistant to paramomycin.

Penny GM, Dutcher SK. Gene dosage of independent dynein arm motor preassembly factors influences cilia assembly in Chlamydomonas reinhardtii. PLoS Genet. 2024 Mar 18;20(3):e1011038. doi: 10.1371/journal.pgen.1011038. PMID: 38498551; PMCID: PMC11020789.)

Desai PB, Freshour JR, Mitchell DR. Chlamydomonas axonemal dynein assembly locus ODA8 encodes a conserved flagellar protein needed for cytoplasmic maturation of outer dynein arm complexes. Cytoskeleton (Hoboken). 2015 Jan;72(1):16-28. doi: 10.1002/cm.21206. Epub 2015 Feb 7. PMID: 25558044; PMCID: PMC4361367.

Locus:
ODA8, AC17, ATG17
Chromosome:
1, 3, 16
Mutation Information:
Predicted Mutation Effect:

CC-6096 oda8; ac17; aphVIII mt+

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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