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CC-6105 pf22; ac17; aphVIII mt-

Name: CC-6105 pf22; ac17; aphVIII mt-
SKU: CC-6105
Availability: InStock

$30.00

From Gervette Penny, Susan Dutcher lab, Washington Univerity in St. Loius, November 2023

Genotype: pf22; ac17; ATG17:aphVIII-TG
Phenotype: Aciliate/short cilia

This is a cross of pf22 CC-1382 with CC-5909. It requires acetate for growth and is resistant to paramomycin

Penny GM, Dutcher SK. Gene dosage of independent dynein arm motor preassembly factors influences cilia assembly in Chlamydomonas reinhardtii. PLoS Genet. 2024 Mar 18;20(3):e1011038. doi: 10.1371/journal.pgen.1011038. PMID: 38498551; PMCID: PMC11020789.

Schmidts M, Freshour J, Loges NT, Dritsoula A, Antony D, Hirst RA, et al. Mutations in the dynein assembly factor PF22 (DNAAF3) cause primary ciliary dyskinesia with absent dynein arms. Cilia 2012 1:1. 2012;1: 1–1. doi:10.1186/2046-2530-1-S1-P101

Locus:
PF22, AC17, ATG17
Chromosome:
1, 3, 16
Mutation Information:
Predicted Mutation Effect:

CC-6105 pf22; ac17; aphVIII mt-

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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