CC-1543 C. eugametos nic-6 mod-1?

$30.00

From C.S. Gowans, University of Missouri, March 1983, his strain N 2028-4

The nic-6 mutant requires nicotinamide or quinolinic acid. mod-1 is a second mutation that blocks utilization of quinolinic acid (in nic-6) and nicotinic acid (in nic-5 and nic-6). The mod-1 phenotype can be abolished by high ionic strength (50 mM KCl or other salts) but not by osmotically active agenes such as glucose, sucrose, or glycerol. Nakamura and Gowans (1972) postulated that the mod-1 mutation might modify calcium transport, with the change in utilization of nicotinic and quinolinic acids being a secondary effect.


Nakamura K, Gowans CS (1965) Genetic Control of Nicotinic Acid Metabolism in Chlamydomonas Eugametos. Genetics 51:931-945

Nakamura K, Gowans CS (1967) Ionic remediability of a mutational transport defect in Chlamydomonas. J Bacteriol 93:1185-1187

Nakamura K, Gowans CS (1972) A modifier of a nic gene in Chlamydomonas. Can J Gen Cytol 14:733