CC-2919 adf1 mt+

$30.00

From Ursula Goodenough, Washington University, July 1993

Phenotype: impaired flagellar autotomy

The adf1 mutation was isolated by Saito and Goodenough, as a second mutation in a stock of imp4. Quarmby has found that adf1 deflagellates in response to mastoparan, but not in response to acid, and that adf1 cells are defective in acid-activated Ca2+ influx.


Quarmby LM, Hartzell HC (1994) Two distinct, calcium-mediated, signal transduction pathways can trigger deflagellation in Chlamydomonas reinhardtii. J Cell Biol 124:807-815

Crain RC, Yueh YG (1995) Phosphoinositide signalling in plant and algal responses to physiological stimuli. Biochem Soc Trans 23:853-856

Evans JH, Keller LR (1997) Calcium influx signals normal flagellar RNA induction following acid shock of Chlamydomonas reinhardtii. Plant Mol Biol 33:467-481

Evans JH and Keller LR (1997) Receptor-Mediated Calcium Influx in Chlamydomonas reinhardtii. J Euk Microbiol 44:237-245

Finst RJ, Kim PJ, Quarmby LM (1998) Genetics of the deflagellation pathway in Chlamydomonas. Genetics 149:927-936


  • Locus:
  • ADF1
  • Chromosome:
  • 9