* The listed price of $30.00 for cultures and plasmids is for academic and non-profit users. Commercial and industrial users are charged $300.00 for each strain or plasmid and twice the listed price for media components. BACs and fosmids are $50.00 for academic and non-profit users and $500 for commercial/industry. For the Jonikas CLiP mutants, the price is $100.00 each for academic and non-profit users and commercial and industrial users are charged $500.00.

CC-3751 fa2-1 mt+

Name: CC-3751 fa2-1 mt+
SKU: CC-3751
Availability: InStock

$30.00

From Lynne Quarmby and Rip Finst, Emory University, November 1999

Phenotype: impaired flagellar autotomy

Like fa1 (see CC-1370), the fa2 mutants are defective in flagellar autotomy, and fail to sever outer microtuble doublets in response to calcium. The FA2 gene encodes a NIMA-related kinase.

Finst RJ, Kim PJ, Quarmby LM (1998) Genetics of the deflagellation pathway in Chlamydomonas. Genetics 149:927-936

Mahjoub MR, Montpetit B, Zhao L, Finst RJ, Goh B, Kim AC, Quarmby LM (2002) The FA2 gene of Chlamydomonas encodes a NIMA family kinase with roles in cell cycle progression and microtubule severing during deflagellation. J Cell Sci 115:1759-1768

Mahjoub MR, Qasim Rasi M, Quarmby LM (2004) A NIMA-related kinase, Fa2p, localizes to a novel site in the proximal cilia of Chlamydomonas and mouse kidney cells. Mol Biol Cell 15:5172-5186

Locus:
FA2
Chromosome:
7

CC-3751 fa2-1 mt+

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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