CC-3960 arg7 crr1-2::ble mt+
$30.00
From Jeffrey Moseley in Sabeeha Merchant’s laboratory, UCLA, June 2002
Phenotype: grows poorly and requires acetate on copper-depleted medium
This is a ble-tagged allele at the CRR1 locus which encodes a copper homeostasis regulator.
Eriksson M, Moseley JL, Tottey S, Del Campo JA, Quinn J, Kim Y, Merchant S (2004) Genetic dissection of nutritional copper signaling in chlamydomonas distinguishes regulatory and target genes. Genetics 168:795-807
Lambertz C, Hemschemeier A, Happe T (2010) Anaerobic expression of the ferredoxin-encoding FDX5 gene of Chlamydomonas reinhardtii is regulated by the Crr1 transcription factor. Eukaryot Cell 9:1747-1754
Sommer F, Kropat J, Malasarn D, Grossoehme NE, Chen X, Giedroc DP, Merchant SS (2010) The CRR1 nutritional copper sensor in Chlamydomonas contains two distinct metal-responsive domains. Plant Cell 22:4098-4113