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CC-4181 bld10-1 arg7 mt-

Name: CC-4181 bld10-1 arg7 mt-
SKU: CC-4181
Availability: InStock

$30.00

From Masafumi Hirono, University of Tokyo, December 2007

Phenotype: lacks flagella, does not mate; requires arginine

The BLD10 locus encodes a coiled-coil protein localized to the cartwheel structure at the proximal end of the basal body. Null mutants at this locus have no basal bodies or flagella. Alleles in which a truncated protein is made have abnormal basal bodies in which the 9-fold symmetry is altered.

Marshall WF (2007) Centriole assembly: the origin of nine-ness. Curr Biol 7, R1057-R1059

Hiraki M, Nakazawa Y, Kamiya R, Hirono M (2007) Bld10p constitutes the cartwheel-spoke tip and stabilizes the 9-fold symmetry of the centriole. Curr Biol 17:1778-1783

Locus:
BLD10
Chromosome:
10

Marshall WF (2007) Centriole assembly: the origin of nine-ness. Curr Biol 7, R1057-R1059

Hiraki M, Nakazawa Y, Kamiya R, Hirono M (2007) Bld10p constitutes the cartwheel-spoke tip and stabilizes the 9-fold symmetry of the centriole. Curr Biol 17:1778-1783

CC-4181 bld10-1 arg7 mt-

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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