CC-4752 rbcS1-Y32R mt-

$30.00

From Robert J. Spreitzer, University of Nebraska, July 2014

Using established methods of directed mutagenesis and nuclear-gene transformation of rbcS∆-T60-3 mt- (CC-4415) (Genkov and Spreitzer 2009), Todor Genkov in Spreitzer’s group created a Y32R substitution in the Rubisco small subunit, which causes a decrease in Rubisco holoenzyme stability (Genkov and Spreitzer, unpublished). This strain has been maintained with acetate medium in darkness to prevent selection for secondary mutations that may improve Rubisco function or stability.


Genkov T, Spreitzer RJ (2009) Highly conserved small subunit residues influence Rubisco large subunit catalysis. J Biol Chem 284:30105-30112


  • Locus:
  • RBCS1
  • Chromosome:
  • 2