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CC-477 bld1-1

Name: CC-477 bld1-1
SKU: CC-477
Availability: InStock

$30.00

From Ursula Goodenough, Harvard University, March 1978

Phenotype: lacks flagella, does not mate

The bld or bald mutants were recovered as nonmating mutants in Goodenough’s laboratory, and were subsequently shown to lack flagella. This is the original bld1 mutant.

The BLD1 locus encodes intraflagellar transport protein IFT52, a homolog of C. elegans osm-6.

Pasquale SM, Goodenough UW (1987) Cyclic AMP functions as a primary sexual signal in gametes of Chlamydomonas reinhardtii. J Cell Biol 105:2279-2292

Brazelton WJ, Amundsen CD, Silflow CD, Lefebvre PA (2001) The bld1 mutation identifies the Chlamydomonas osm-6 homolog as a gene required for flagellar assembly. Curr Biol 11:1591-1594

Deane JA, Cole DG, Seeley ES, Diener DR, Rosenbaum JL (2001) Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles. Curr Biol 11:1586-1590

Locus:
BLD1 [IFT52]
Chromosome:
4

CC-477 bld1-1

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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