CC-5237 hydEF1::pSP124s-HYDEF mt+ rescue [isolate #9]

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From Iftach Yacoby, Tel Aviv University, April 2016

Random insertion of the gemonic part of HydEF to rescue the hydEF1 mutant (CC-5128) using the plasmid pSP124s_bleR_HYDEF_KpnI_ins_ (13118bp). Hydrogen production was validated. This was a repeated rescue using the original plasmid from Posewitz et al.


Posewitz MC, King PW, Smolinski SL, Zhang L, Seibert M, Ghirardi ML (2004) Discovery of two novel radical S-adenosylmethionine proteins required for the assembly of an active [Fe] hydrogenase. J Biol Chem. 279:25711-20


  • Locus:
  • HYDEF1
  • Chromosome:
  • 6