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CC-5367 PAM amiRNA2 #3 mt+

Name: CC-5367 PAM amiRNA2 #3 mt+
SKU: CC-5367
Availability: InStock

$30.00

From Steven King, University of Connecticut Health Center, June 2017

This is an amiRNA strain with reduced levels of the enzyme peptidylglycine alpha-amidating monooxygenase (PAM; Cre03.g152850). This strain exhibits a strong knockdown of PAM expression to ~30% of control levels resulting in aflagellate cells.

Kumar D, Blaby-Haas CE, Merchant SS, Mains RE, King SM, Eipper BA (2016) Early eukaryotic origins for cilia-associated bioactive peptide-amidating activity. J Cell Sci 129:943-56

Kumar D, Strenkert D, Patel-King RS, Leonard MT, Merchant SS, Mains RE, King SM, Eipper BA (2017) A bioactive peptide amidating enzyme is required for ciliogenesis. eLife 10.7554/eLife.25728

Kumar D, Blaby-Haas CE, Merchant SS, Mains RE, King SM, Eipper BA (2016) Early eukaryotic origins for cilia-associated bioactive peptide-amidating activity. J Cell Sci 129:943-56

Kumar D, Strenkert D, Patel-King RS, Leonard MT, Merchant SS, Mains RE, King SM, Eipper BA (2017) A bioactive peptide amidating enzyme is required for ciliogenesis. eLife 10.7554/eLife.25728

CC-5367 PAM amiRNA2 #3 mt+

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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