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CC-6007 dlu1-1 ida1 [#6c]

Name: CC-6007 dlu1-1 ida1 [#6c]
SKU: CC-6007
Availability: InStock

$30.00

From Miho Sakato-Antoku, Stephen M King lab, University of Connecticut Health, May 2023

Phenotype: lacks outer arm dynein light chain LC1 and inner arm dynein I1/f; paromomycin-resistant; tends to form palmelloid cells

This mutant was obtained by crossing dlu1-1 (strain 5a, CC-6005) and ida1 (CC-2665). It is designated as strain 6c in King lab.

Kamiya R, Kurimoto E, Muto E. Two types of Chlamydomonas flagellar mutants missing different components of inner-arm dynein. J Cell Biol. 1991 Feb;112(3):441-7. doi: 10.1083/jcb.112.3.441. PMID: 1825085; PMCID: PMC2288841.

Sakato-Antoku M, King SM. Outer-arm dynein light chain LC1 is required for normal motor assembly kinetics, ciliary stability, and motility. Mol Biol Cell. 2023 Jun 1;34(7):ar75. doi: 10.1091/mbc.E23-03-0104. Epub 2023 May 3. PMID: 37133971; PMCID: PMC10295483.

Locus:
DLU1 [DLU1], IDA1 [DHC1]
Chromosome:
2, 12
Mutation Information:
Predicted Mutation Effect:

CC-6007 dlu1-1 ida1 [#6c]

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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