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CC-6093 oda5; ac17; aphVIII mt+

Name: CC-6093 oda5; ac17; aphVIII mt+
SKU: CC-6093
Availability: InStock

$30.00

From Gervette Penny, Susan Dutcher lab, Washington Univerity in St. Loius, November 2023

Genotype: oda5; ac17; ATG17:aphVIII-TG
Phenotype: Impaired mobility

This is a cross of oda5 CC-2236 with CC-5909. It requires acetate for growth and is resistant to paramomycin.

Penny GM, Dutcher SK. Gene dosage of independent dynein arm motor preassembly factors influences cilia assembly in Chlamydomonas reinhardtii. PLoS Genet. 2024 Mar 18;20(3):e1011038. doi: 10.1371/journal.pgen.1011038. PMID: 38498551; PMCID: PMC11020789.

Wirschell M, Pazour G, Yoda A, Hirono M, Kamiya R, Witman GB. Oda5p, a novel axonemal protein required for assembly of the outer dynein arm and an associated adenylate kinase. Mol Biol Cell. 2004 Jun;15(6):2729-41. doi: 10.1091/mbc.e03-11-0820. Epub 2004 Apr 2. PMID: 15064350; PMCID: PMC420097.

Locus:
ODA5, AC17, ATG17
Chromosome:
7, 3,16
Mutation Information:
Predicted Mutation Effect:

CC-6093 oda5; ac17; aphVIII mt+

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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