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CC-6097 oda9; ac17; aphVIII mt+

Name: CC-6097 oda9; ac17; aphVIII mt+
SKU: CC-6097
Availability: InStock

$30.00

From Gervette Penny, Susan Dutcher lab, Washington Univerity in St. Loius, November 2023

Genotype: oda9; ac17; ATG17:aphVIII-TG
Phenotype: Impaired mobility

This is a cross of oda9 CC-2244 with CC-5909. It requires acetate for growth and is resistant to paramomycin.

Penny GM, Dutcher SK. Gene dosage of independent dynein arm motor preassembly factors influences cilia assembly in Chlamydomonas reinhardtii. PLoS Genet. 2024 Mar 18;20(3):e1011038. doi: 10.1371/journal.pgen.1011038. PMID: 38498551; PMCID: PMC11020789.

Wilkerson CG, King SM, Koutoulis A, Pazour GJ, Witman GB. The 78,000 M(r) intermediate chain of Chlamydomonas outer arm dynein isa WD-repeat protein required for arm assembly. J Cell Biol. 1995 Apr;129(1):169-78. doi: 10.1083/jcb.129.1.169. PMID: 7698982; PMCID: PMC2120364.

Fowkes ME, Mitchell DR. The role of preassembled cytoplasmic complexes in assembly of flagellar dynein subunits. Mol Biol Cell. 1998 Sep;9(9):2337-47. doi: 10.1091/mbc.9.9.2337. PMID: 9725897; PMCID: PMC25499.

Locus:
ODA9, AC17, ATG17
Chromosome:
12, 3, 16
Mutation Information:
Predicted Mutation Effect:

CC-6097 oda9; ac17; aphVIII mt+

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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