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CC-6123 ida10-2 mt+ [G5]

Name: CC-6123 ida10-2 mt+ [G5]
SKU: CC-6123
Availability: InStock

$30.00

From Ryosuke Yamamoto, Osaka University-Japan, April 2024

Originally a CLiP mutant with the non-AphVIII ida10-2 mutation, backcrossed to the 137C wild-type strain to isolate the ida10-2 mutation. This is a dynein preassembly-deficient mutant.

Yamamoto R, Hirono M, Kamiya R. Discrete PIH proteins function in the cytoplasmic preassembly of different subsets of axonemal dyneins. J Cell Biol. 2010 Jul 12;190(1):65-71. doi: 10.1083/jcb.201002081. Epub 2010 Jul 5. PMID: 20603327; PMCID: PMC2911668.

Yamamoto R, Yanagi S, Nagao M, Yamasaki Y, Tanaka Y, Sale WS, Yagi T, Kon T. Mutations in PIH proteins MOT48, TWI1 and PF13 define common and unique steps for preassembly of each, different ciliary dynein. PLoS Genet. 2020 Nov 3;16(11):e1009126. doi: 10.1371/journal.pgen.1009126. PMID: 33141819; PMCID: PMC7608865.

Locus:
IDA10/DAP2
Chromosome:
10
Mutation Information:
Predicted Mutation Effect:

CC-6123 ida10-2 mt+ [G5]

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Banner Photo Credit: Chlamydomonas reinhardtii zygotes were stained for immunofluorescence with anti-acetylated tubulin (green), anti-phospholipase D (red), and DAPI (blue) by Karl F. Lechtreck (University of Georgia) and George B. Witman (University of Massachusetts Medical School).

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