CC-6288 ΔVIG1; ΔSRTA mt+ [Δ1A]

$30.00

From Alexander Einhaus, Algae Biotechnology and Bioenergy, Bielefeld University, Germany, June 2025

Background: CC-4350
Origin: CRISPR Cas9-mediated integration of selectable marker
Selectable marker: HygR, Arg7
Initial KO target: VIG1 (Cre09.g393358) – Orthologue of the Vasa intronic gene, ancillary ribosomal component
Second KO target: SRTA (Cre10.g462200) – Sir2-Type Histone Deacetylase


Einhaus A, Krieger A, Köhne L, Rautengarten B, Jacobebbinghaus N, Saudhof M, Baier T, Kruse O. Genome editing of epigenetic transgene silencing in Chlamydomonas reinhardtii. Trends Biotechnol. 2025 May 30:S0167-7799(25)00164-7. doi: 10.1016/j.tibtech.2025.04.019. Epub ahead of print. PMID: 40450408.


Einhaus A, Krieger A, Köhne L, Rautengarten B, Jacobebbinghaus N, Saudhof M, Baier T, Kruse O. Genome editing of epigenetic transgene silencing in Chlamydomonas reinhardtii. Trends Biotechnol. 2025 May 30:S0167-7799(25)00164-7. doi: 10.1016/j.tibtech.2025.04.019. Epub ahead of print. PMID: 40450408.