P-377 cpDNA KpnI-BamHI (2.6 kb) er-u-1a

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Boynton-Gillham laboratory, Duke University, 1991

Chloroplast DNA KpnI-BamHI (2.6 kb) in pUC18; 5S and 3′ end of 23S with er-u-1a mutation

host strain: JM109
amp resistant

 

More information

Strain: CC-64 er-u-1a

Insert: KpnI-BamHI (2.6 kb)

Genes present: 23S rRNA, 3′ end

Vector: pUC18

Bacterial host strain: JM109

Selectable marker: amp-r

Origin: Scott Newman in Boynton/Gillham lab, 1991

P-377

This is a subclone of P-321, which was a ligation of sequences from CC-2534 and CC-64. The fragment remaining in this subclone derives mainly from CC-64.

The er-u-1a mutation is a C > T change at bp 2622 in C. reinhardtii 23S rRNA (Lemieux numbering, equivalent to E. coli 2611), conferring resistance to erythromycin.