CC-5858 oda3 oda6::IC2-NG ift20::IFT20-mC mt-

$30.00

From Gui Zhang, Karl Lechtreck lab, University of Georgia, February 2022

This strain was obtained by mating oda3 oda6::IC2-NG and ift20::IFT20-mCherry. The outer dynein arms (ODAs) are tagged on the essential IC2 subunits with mNeonGreen and IFT is visible by IFT20-mCheery expression. ODAs do not assemble in cilia due to the absence of the docking complex in oda3. This allows imaging of ODA transport by IFT.


Dai J, Barbieri F, Mitchell DR, Lechtreck KF. In vivo analysis of outer arm dynein transport reveals cargo-specific intraflagellar transport properties. Mol Biol Cell. 2018 Oct 15;29(21):2553-2565. doi: 10.1091/mbc.E18-05-0291. Epub 2018 Aug 22. PMID: 30133350; PMCID: PMC6254574.


  • Locus:
  • ODA3 [DCC1], ODA6 [DIC2], IFT20
  • Chromosome:
  • 17, 12, 2
  • Mutation Information:
  • Predicted Mutation Effect: